Compassionate, evidence-based care for all causes of female infertility — PCOS, endometriosis, blocked tubes, low ovarian reserve & more. Personalised plans, world-class technology.
Female infertility is defined as the inability to conceive after 12 months of regular, unprotected intercourse (or 6 months if the woman is over 35). It affects approximately 1 in 6 couples worldwide and accounts for about 40% of all infertility cases.
The causes are diverse — from ovulation disorders and blocked fallopian tubes to endometriosis, uterine abnormalities, hormonal imbalances, and age-related decline in egg quality and quantity. Many women have no obvious symptoms, making specialist evaluation essential.
At Matrushri, our gynaecologists and reproductive endocrinologists perform a comprehensive assessment to identify the exact cause and design a personalised treatment plan that maximises your chances of a healthy pregnancy.
Identifying the precise cause is the foundation of effective treatment. Our specialists evaluate every possible factor.
The most common cause — accounting for 25% of cases. PCOS, hyperprolactinaemia, thyroid disorders, and premature ovarian failure all disrupt normal ovulation.
Most CommonHormonal imbalance causing irregular periods, excess androgens, and multiple small ovarian cysts. The leading cause of anovulatory infertility in India.
Very CommonTissue similar to the uterine lining grows outside the uterus, causing inflammation, scarring, and distortion of pelvic anatomy. Affects 1 in 10 women of reproductive age.
10% of WomenObstructions prevent sperm from reaching the egg and embryo from reaching the uterus. Often caused by PID, previous infections, or endometriosis.
StructuralFibroids, polyps, adhesions (Asherman's syndrome), or congenital uterine malformations can interfere with implantation and early pregnancy.
StructuralReduced quantity or quality of eggs, often age-related but also caused by genetics, prior surgery, or chemotherapy. Diagnosed via AMH and antral follicle count.
Age-RelatedThyroid dysfunction, hyperprolactinaemia, adrenal disorders, and abnormal FSH/LH ratios can all disrupt the hormonal cascade needed for ovulation.
HormonalTurner syndrome, Fragile X premutation, chromosomal translocations, and other genetic conditions can affect egg quality, ovarian function, and implantation.
GeneticIn 10–15% of cases, all standard tests appear normal. Advanced testing for subtle immune, genetic, or endometrial factors may reveal the underlying cause.
10–15% of CasesMany women with infertility have no symptoms beyond difficulty conceiving. These warning signs warrant a specialist evaluation:
Cycles shorter than 21 days, longer than 35 days, or completely absent often indicate an ovulation disorder such as PCOS or hypothalamic dysfunction.
Severe menstrual cramps, very heavy bleeding, or pain during intercourse (dyspareunia) may indicate endometriosis or uterine fibroids.
Chronic lower abdominal or pelvic pain — especially around ovulation or menstruation — can signal endometriosis, pelvic inflammatory disease, or ovarian cysts.
Sudden weight gain or difficulty losing weight alongside irregular periods may indicate PCOS or thyroid dysfunction, both of which affect fertility.
Two or more consecutive pregnancy losses indicate an underlying issue — chromosomal, uterine, immune, or hormonal — that requires specialist investigation.
Excess facial hair (hirsutism), acne, hair loss, or milky nipple discharge (galactorrhoea) suggest hormonal imbalances affecting ovulation and fertility.
Vasomotor symptoms in younger women may indicate premature ovarian insufficiency (POI) or diminished ovarian reserve, requiring urgent fertility evaluation.
The primary indicator. If you are under 35 and have been trying for 12 months, or over 35 and trying for 6 months, consult a fertility specialist without delay.
A thorough, step-by-step evaluation ensures we identify every factor affecting your fertility — nothing is left to chance.
Detailed review of menstrual history, past pregnancies, surgeries, medications, lifestyle, and family history of fertility conditions.
FSH, LH, estradiol, progesterone, AMH, prolactin, thyroid (TSH, T3, T4), testosterone, and insulin levels assessed on specific cycle days.
Anti-Müllerian Hormone test and transvaginal antral follicle count (AFC) to assess the quantity and quality of remaining eggs.
Transvaginal ultrasound to evaluate uterine structure, endometrial lining, ovarian volume, follicle count, fibroids, polyps, and cysts.
X-ray dye test to assess fallopian tube patency and uterine cavity shape. Detects blockages, adhesions, and structural abnormalities.
Minimally invasive surgical camera examination of the pelvic organs — the gold standard for diagnosing endometriosis and pelvic adhesions.
Camera examination inside the uterine cavity to detect and treat polyps, fibroids, adhesions (Asherman's), and septum — often done alongside treatment.
Karyotype analysis, Fragile X premutation screening, and preimplantation genetic testing (PGT) to identify chromosomal causes of infertility or recurrent loss.
Our specialists are experts in diagnosing and treating every condition that affects female fertility.
PCOS is the leading cause of anovulatory infertility in India, affecting 1 in 5 women of reproductive age. It causes hormonal imbalance, irregular or absent ovulation, and multiple small follicles on the ovaries.
At Matrushri, we offer a comprehensive, individualised approach combining lifestyle intervention, medication, and ART when needed.
Every PCOS patient is different. Our endocrinologists design bespoke stimulation protocols — carefully titrating doses to maximise egg yield while minimising ovarian hyperstimulation syndrome (OHSS) risk.
Endometriosis affects up to 50% of women investigated for infertility. Endometrial-like tissue outside the uterus causes chronic inflammation, scarring, and distortion of pelvic anatomy that impairs fertility.
Our surgeons are trained in advanced endometriosis excision techniques, removing lesions thoroughly while preserving ovarian tissue and maximising post-surgical fertility.
Tubal blockage prevents fertilisation and is one of the most common structural causes of female infertility. HSG and laparoscopy confirm the location and extent of blockage.
We combine HSG for initial assessment with diagnostic laparoscopy for definitive diagnosis and simultaneous treatment, minimising the time to intervention and maximising your chances of natural conception.
Diminished ovarian reserve means fewer eggs of lower quality, reducing the chances of natural conception. Age is the most common cause, but genetics, surgery, and prior chemotherapy also play a role.
Our reproductive endocrinologists design aggressive yet safe stimulation protocols for poor responders, with close monitoring to retrieve every available egg and optimise the chances of a successful pregnancy.
Fibroids, endometrial polyps, intrauterine adhesions (Asherman's syndrome), and congenital uterine septum can all prevent implantation or cause recurrent pregnancy loss.
Most uterine abnormalities can be corrected through hysteroscopy — a camera inserted into the uterus, eliminating the need for external incisions, with rapid recovery and same-day discharge in most cases.
Two or more consecutive miscarriages affect approximately 1–2% of couples. A thorough investigation can identify a treatable cause in up to 50% of cases.
We leave no stone unturned — investigating chromosomal, uterine, immune, thrombophilic, and hormonal factors. Our RPL clinic provides dedicated support and a clear management plan for every couple.
From simple ovulation induction to advanced IVF — we offer the full spectrum of evidence-based treatments tailored to your diagnosis.
Oral medications (clomiphene, letrozole) or injectable gonadotropins stimulate the ovaries to produce and release one or more eggs — combined with timed intercourse or IUI.
Learn More →Washed, prepared sperm is placed directly into the uterus around the time of ovulation. A minimally invasive first-line ART option for mild infertility.
Learn More →Eggs are retrieved after controlled ovarian stimulation and fertilised with sperm in our Class 1000 lab. Resulting embryos are transferred to the uterus after 3–5 days.
Learn More →A single healthy sperm is injected directly into each egg — ideal when there is also a male factor component, or when standard IVF fertilisation has failed.
Learn More →Minimally invasive surgical procedures to diagnose and simultaneously treat endometriosis, fibroids, polyps, adhesions, and blocked tubes — often restoring natural fertility.
Learn More →Egg or embryo freezing (vitrification) for women wishing to delay pregnancy, or those facing cancer treatment. Preserves your options for the future.
Learn More →Embryos created through IVF are tested for chromosomal abnormalities (PGT-A) or specific genetic conditions (PGT-M) before transfer, reducing miscarriage risk.
Learn More →When a woman's own egg quality or quantity is insufficient, donor eggs from a screened, matched donor are fertilised and transferred — offering excellent success rates.
Learn More →Targeted hormone therapy for thyroid disorders, hyperprolactinaemia, luteal phase deficiency, and other hormonal causes — often restoring natural fertility without ART.
Learn More →From your first call to a positive pregnancy test — here is how we guide you every step of the way.
Call us or fill the form below. Our patient coordinators will schedule your first appointment at the nearest Matrushri clinic — often within 24–48 hours.
Our gynaecologist and reproductive endocrinologist conduct a full evaluation — medical history, hormonal tests, pelvic ultrasound, and review of any prior investigations.
Based on initial findings, we may recommend AMH, HSG, 3D ultrasound, laparoscopy, hysteroscopy, or genetic testing to pinpoint the exact cause.
Your specialist presents a clear, tailored treatment plan — explaining every option, success rates, timelines, and costs. You make the decision together.
Whether ovulation induction, surgery, or IVF — you receive dedicated monitoring with regular ultrasounds, blood tests, and direct access to your care team throughout.
A positive pregnancy test is just the beginning. We provide early pregnancy scans, ongoing support, and a warm handover to your obstetric team for a safe, healthy pregnancy.
We combine clinical excellence with genuine compassion — because every woman's journey deserves both.
Dedicated gynaecologists, reproductive endocrinologists, embryologists, and counsellors — all experienced in female infertility and committed to personalised care.
Our internationally certified clean-room IVF lab maintains optimal conditions for egg retrieval, fertilisation, ICSI, embryo culture, and cryopreservation.
From ovulation induction and laparoscopy to IVF, PGT, donor eggs, and fertility preservation — complete female fertility care without referrals elsewhere.
No protocols are ever copy-pasted. Every plan is designed individually after thorough evaluation, with shared decision-making and clear explanation of every step.
Fertility treatment is emotionally demanding. Our counsellors provide dedicated psychological support throughout your journey — because mental wellbeing matters.
With centres in Vijayawada, Hyderabad, Secunderabad, Guntur, Karimnagar, Rajahmundry, Warangal, and more — expert care is always close to home.
Real patients, real outcomes — thousands of women have trusted Matrushri on their path to motherhood.
"After 4 years of trying and 2 failed IVF cycles elsewhere, Matrushri diagnosed my endometriosis correctly for the first time. After laparoscopic surgery and one IVF cycle, I am now 8 weeks pregnant. I cannot thank this team enough."
"I was told by another clinic that donor eggs were my only option due to PCOS and low AMH. The doctors at Matrushri designed a gentle IVF protocol and retrieved 6 eggs. I am now a proud mother of twins!"
"Three miscarriages left us devastated. Matrushri found that I had a uterine septum and antiphospholipid syndrome. After hysteroscopic surgery and the right medications, our fourth pregnancy was successful."
We offer the full spectrum of fertility treatments — from the simplest to the most advanced — customised to each couple's unique medical profile.
Our specialists diagnose and manage a wide range of conditions affecting female and male fertility with evidence-based, compassionate care.