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Matrushri
Fertility Centers Consultancy (Agencies)
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+91 92473 51372 (Hyderabad)
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+91 81258 17240 (Tirupati)
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Infertility Treatment
🌸 Female Infertility 💙 Male Infertility 🧫 IVF – In Vitro Fertilisation 🔬 IUI – Intrauterine Insemination 🧬 ICSI ⚗️ PICSI 🫧 Blastocyst Culture 🧩 Genetics Program (PGT/PGS) ❄️ Fertility Preservation
Diagnostic Tests — Male
🧬 Semen Analysis 🔬 DNA Fragmentation Test 🧪 Hormone Profile 🩺 Testicular Biopsy 🫧 Anti-Sperm Antibody Test
Diagnostic Tests — Female
💉 AMH Test 🩺 HSG Test 🔬 Hormonal Panel 🫃 Pelvic Ultrasound
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ℹ️ About Us
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📍 Hyderabad Clinic 📍 Tirupati Clinic
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💙 Expert Male Fertility Care

Best Male Infertility
Treatment Centre

Advanced diagnosis and personalised treatment for all causes of male infertility — from low sperm count to azoospermia. TESA, Micro-TESE, PESA, MESA & ART under one roof.

50%
Infertility cases involve
male factors
22+
Fertility super-specialists
on our team
11
Clinics across
AP & Telangana
Male infertility consultation
🏆
No.1 Fertility Centre in AP & Telangana
Understanding the Condition

What is Male Infertility?

Male infertility is a condition where a couple cannot conceive due to problems with the male partner's reproductive health. It accounts for nearly half of all infertility cases globally, making it just as common as female infertility.

At Matrushri Fertility Centers, our andrologists and fertility specialists perform a thorough evaluation including medical history review, physical examination, semen analysis, hormonal testing, scrotal ultrasound, and genetic testing to identify the exact cause before designing a personalised treatment plan.

Treatments are customised and recommended only after identifying the underlying problem, ensuring the highest possible success rates.

🧬 Genetic Testing
🔬 Semen Analysis
💉 Hormone Profiling
🩺 Scrotal Ultrasound
🏥 Personalised Plans
🤝 Couple Counselling
Doctor consultation
Root Causes

Common Causes of Male Infertility

Understanding the root cause is the first step towards effective treatment. Our experts diagnose and address all known causes.

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Varicocele

Enlarged veins in the scrotum cause increased testicular temperature, reducing sperm production and quality. One of the most common and treatable causes.

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Low Sperm Count (Oligospermia)

Fewer than 15 million sperm per mL of semen. Can result from hormonal imbalances, infections, lifestyle factors, or genetic conditions.

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Azoospermia

Complete absence of sperm in the semen. Can be obstructive (blockage) or non-obstructive (production failure) — both treatable with advanced techniques.

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Hormonal Imbalances

Low testosterone, elevated FSH/LH, thyroid disorders, or hyperprolactinaemia can all impair sperm production and function.

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Blocked Ducts

Obstructions in the epididymis, vas deferens, or ejaculatory duct prevent sperm from reaching semen. Often correctable surgically.

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Genetic Factors

Y-chromosome microdeletions, Klinefelter syndrome, and other chromosomal abnormalities can impact sperm production and quality.

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Infections

Sexually transmitted infections, orchitis, or epididymitis can damage sperm-producing tissue or block sperm transport pathways.

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Lifestyle Factors

Smoking, alcohol, drug use, obesity, excessive heat exposure, and stress all negatively affect sperm quality and quantity.

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Anti-Sperm Antibodies

Immune system attacks sperm, reducing motility and ability to fertilise an egg. Identified through specialised immunological testing.

Signs to Watch For

Symptoms of Male Infertility

Many men with infertility have no obvious symptoms other than difficulty conceiving. However, these signs may indicate an underlying issue:

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Unable to Conceive After 1 Year

The primary indicator — if a couple has been trying to conceive for over 12 months without success, male factor should be investigated.

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Pain or Swelling in Testicular Area

Discomfort, swelling, or a lump in or around the testes may indicate varicocele, infection, or other conditions affecting fertility.

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Reduced Sexual Desire or Dysfunction

Low libido, erectile dysfunction, or ejaculation problems may point to hormonal imbalances affecting both sexual function and fertility.

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Decreased Body or Facial Hair

Chromosomal or hormonal abnormalities can cause reduced body or facial hair growth, a sign of low testosterone or other conditions.

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Abnormal Ejaculation

Very low volume of ejaculate, absent ejaculation (retrograde ejaculation), or milky urine after orgasm may indicate blocked or absent ducts.

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Small or Undescended Testicles

Small testicles or a history of undescended testes (cryptorchidism) are associated with impaired sperm production from a young age.

How We Diagnose

Our Diagnostic Process

Accurate diagnosis is the foundation of effective treatment. Our step-by-step evaluation leaves nothing to chance.

1

Medical History & Consultation

Detailed review of medical history, lifestyle, sexual habits, prior infections, surgeries, and medications.

2

Physical Examination

Examination of genitals for varicocele, undescended testes, structural abnormalities, and other physical indicators.

3

Semen Analysis

Comprehensive sperm count, motility, morphology, volume, and DNA fragmentation assessment in our Class 1000 IVF lab.

4

Hormone Testing

Blood tests for FSH, LH, testosterone, prolactin, thyroid function, and other hormones governing sperm production.

5

Scrotal Ultrasound

High-resolution imaging to detect varicoceles, blockages, tumours, or structural abnormalities in the testes and ducts.

6

Genetic Testing

Y-chromosome microdeletion analysis, karyotype testing, and CFTR gene mutation screening where indicated.

7

Urine Analysis

Post-ejaculation urinalysis to detect retrograde ejaculation and rule out urinary tract infections.

8

Testicular Biopsy

When azoospermia is confirmed, biopsy determines if sperm production is occurring and guides sperm retrieval strategy.

Treatment Options

Advanced Treatment Approaches

Our multi-disciplinary team offers the full spectrum of male infertility treatments — from medication to cutting-edge surgical sperm retrieval.

Medical & Hormonal Treatment

Many causes of male infertility can be effectively treated with medication alone, particularly when a hormonal imbalance or infection is the root cause.

  • Hormone therapy for low testosterone or FSH/LH imbalances
  • Antibiotic treatment for reproductive tract infections
  • Antioxidant supplements to improve sperm quality & DNA integrity
  • Medications to treat retrograde ejaculation
  • Thyroid hormone replacement where applicable
  • Lifestyle counselling — diet, exercise, stress management
Treatment Highlight

Targeted Hormonal Therapy

Our endocrinologists design precise hormonal protocols to restore natural sperm production. Regular monitoring ensures optimal response and minimises side effects.

Non-invasive Personalised Protocol Monitored

Surgical Interventions

When obstructions, varicoceles, or structural issues are the cause, surgical correction can restore natural fertility or enable sperm retrieval for ART.

  • Varicocelectomy — repair of enlarged scrotal veins
  • Vasovasostomy — reversal of vasectomy
  • Vasoepididymostomy — bypass of epididymal blockage
  • Transurethral Ejaculatory Duct Resection (TURED)
  • Varicocele embolisation — minimally invasive alternative
  • Cryptorchidism correction in early adulthood
Performed In-House

Dedicated Operation Theatre

All surgical procedures are performed in our state-of-the-art operation theatre by experienced urologists and andrologists, with full post-operative care.

Day Procedure Expert Surgeons Full Aftercare

TESA — Testicular Sperm Aspiration

TESA is a minimally invasive sperm retrieval procedure used when sperm are absent in the ejaculate but are being produced in the testes.

  • Performed under local anaesthesia as an outpatient procedure
  • A fine needle is inserted into the testis to aspirate sperm
  • Retrieved sperm is used directly with ICSI
  • Ideal for obstructive azoospermia cases
  • Quick recovery — most men resume normal activity within 1–2 days
  • Can be combined with IVF for same-day fertilisation
Minimally Invasive

TESA at Matrushri

Our andrologists perform TESA using ultrasound guidance for maximum precision and minimal discomfort. Sperm retrieved are cryopreserved or used fresh for ICSI in our Class 1000 lab.

Outpatient Local Anaesthesia High Success

Micro-TESE — Microsurgical Sperm Extraction

Micro-TESE is the gold-standard sperm retrieval technique for non-obstructive azoospermia, using an operating microscope to identify sperm-producing tubules.

  • Performed under general anaesthesia with an operating microscope
  • Precisely identifies tubules most likely to contain sperm
  • Up to 3× higher sperm retrieval rates than conventional TESE
  • Minimal damage to testicular tissue
  • Recommended when conventional TESA fails
  • Retrieved sperm cryopreserved for future IVF/ICSI cycles
Gold Standard

Micro-TESE at Matrushri

Our microsurgical team uses high-powered operating microscopes to dramatically improve sperm retrieval success in men with non-obstructive azoospermia — even in the most challenging cases.

Microscope Guided Highest Success Tissue Sparing

PESA & MESA — Epididymal Sperm Retrieval

PESA (Percutaneous Epididymal Sperm Aspiration) and MESA (Microsurgical Epididymal Sperm Aspiration) retrieve sperm directly from the epididymis for use in ICSI.

  • PESA: needle aspiration of epididymal fluid — quick and minimally invasive
  • MESA: microsurgical dissection of epididymal tubules for higher yield
  • Ideal for obstructive azoospermia (congenital absence of vas deferens, post-vasectomy)
  • Retrieved sperm can be cryopreserved for multiple cycles
  • Performed alongside IVF/ICSI for coordinated treatment
  • Carried out by experienced microsurgeons
Epididymal Retrieval

PESA & MESA at Matrushri

Our andrologists select between PESA and MESA based on the individual patient's anatomy and diagnosis, maximising sperm yield and quality for the best IVF/ICSI outcomes.

PESA / MESA Cryopreservation Expert Andrologists

Assisted Reproductive Technologies (ART)

When natural conception or surgical correction is not possible, ART offers highly effective pathways to parenthood using retrieved or ejaculated sperm.

  • IUI (Intrauterine Insemination) — for mild male factor infertility
  • IVF (In Vitro Fertilisation) — fertilisation outside the body
  • ICSI (Intracytoplasmic Sperm Injection) — single sperm injected directly into egg
  • PICSI — physiological ICSI using hyaluronan-binding for sperm selection
  • Sperm cryopreservation — banking for future use
  • Donor sperm — when no sperm can be retrieved
Class 1000 IVF Lab

World-Class ART at Matrushri

Our Class 1000 IVF laboratory meets international clean-room standards, ensuring optimal embryo development. Combined with expert embryologists, we deliver industry-leading success rates.

IVF + ICSI Class 1000 Lab High Success Rates
Why Matrushri

Why Choose Matrushri for Male Infertility?

We combine clinical expertise, cutting-edge technology, and compassionate care to give every man the best chance of fatherhood.

🏥

Expert Andrology Team

Dedicated andrologists, urologists, and reproductive endocrinologists with decades of combined experience in male infertility diagnosis and treatment.

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Class 1000 IVF Laboratory

State-of-the-art laboratory meeting international clean-room standards, with advanced equipment for semen analysis, ICSI, and embryo culture.

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Advanced Genetic Testing

Comprehensive genetic evaluation including Y-chromosome analysis, karyotyping, and CFTR mutation screening to identify hereditary causes.

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All Treatments Under One Roof

From medication and varicocelectomy to TESA, Micro-TESE, and IVF/ICSI — complete male infertility care without referrals elsewhere.

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Personalised Treatment Plans

No two patients are the same. Every treatment plan is designed individually, based on thorough diagnosis and shared decision-making with the couple.

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Holistic Couple Support

Emotional counselling, nutritional guidance, lifestyle support, and dedicated patient coordinators throughout every step of the fertility journey.

Common Questions

Frequently Asked Questions

What is the most common cause of male infertility?
Varicocele (enlarged veins in the scrotum) is the most common reversible cause, found in about 40% of infertile men. Low sperm count, poor sperm motility, and azoospermia are also very common. A thorough evaluation is essential to pinpoint the exact cause.
Can azoospermia (zero sperm count) be treated?
Yes. Obstructive azoospermia (blocked ducts) can often be surgically corrected or sperm retrieved via TESA, PESA, or MESA. Non-obstructive azoospermia (production failure) can be addressed with Micro-TESE, which finds sperm in up to 50–60% of cases even when conventional methods fail.
What is the difference between TESA and Micro-TESE?
TESA uses a fine needle to aspirate sperm from the testis — quick and minimally invasive, best for obstructive azoospermia. Micro-TESE uses an operating microscope to identify sperm-producing tubules in the testis — more involved but offers up to 3× higher success for non-obstructive azoospermia.
Is male infertility treatment covered by insurance?
Coverage varies by insurer and policy. Diagnostic tests (semen analysis, hormone tests) are often covered. Surgical procedures like varicocelectomy may be covered. IVF/ICSI and ART procedures typically require specific fertility coverage. Our patient coordinators can help you navigate insurance options.
How long does male infertility treatment take?
Timeline varies by treatment type. Medical therapy for hormonal issues may take 3–6 months to show results. Surgical corrections like varicocelectomy may improve sperm parameters within 3–6 months. Sperm retrieval procedures (TESA, Micro-TESE) are performed on the day of IVF/ICSI and results are immediate.
Can lifestyle changes improve male fertility?
Yes, significantly. Quitting smoking, reducing alcohol, maintaining a healthy weight, managing stress, avoiding excessive heat (hot tubs, saunas), and taking antioxidant supplements can all improve sperm quality and count within 2–3 months (one full sperm production cycle).

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